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Abstract
Objective: In this study, our aim is to investigate the possible protective effects of melatonin on potential damage caused by 2600 MHz radiofrequency (RF) radiation exposure on epididymis.
Materials and Methods: 36 Wistar Albino male rats were divided into six groups. Group 1: Control, Group 2: Sham Control (mirror of RF exposure), Group 3: Sham Melatonin (mirror of RF exposure and melatonin injection), Group 4: Melatonin (melatonin injection), Group 5: RF (2600 MHz RF exposure), Group 6: RF and Melatonin (2600 MHz RF exposure and melatonin injection). During the experiment, body weights were measured and at the end of the 30-day experimental period, epididymis tissues were collected and examined with Hematoxylin-Eosin.
Results: Epididymis was distinguished in normal histological appearance in the Control, Sham Control, Sham Melatonin and Melatonin groups. In the RF group, some structural degenerations were observed such as irregular tubule profile, deterioration and vacuolization in epithelium, loss of stereocilia, seperation in lateral and basal junctions of epithelium and immature sperm formation. In the RF and Melatonin group, the general histological appearance was found to be similar to the control groups except for some continuing degenerations.
Conclusion: Taken together, 2600 MHz RF radiation exposure caused some structural degenerations on epididymis and melatonin administration provided therapeutic effects on these degenerations.
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Article Type: Original Article
EUROPEAN J MED ED TE, Volume 14, Issue 1, March 2021, Article No: em2102
https://doi.org/10.30935/ejmets/9685
Publication date: 04 Feb 2021
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Article Downloads: 1160
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